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HCM and A-fib


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Lisa Salberg Find out more about Lisa Salberg
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  • HCM and A-fib

    Medicine & Law Weekly via LawRx.com via NewsRx.com and NewsRx.net
    Medicine & Law Weekly

    December 24, 2004


    LENGTH: 365 words

    Left atrial function is a strong predictor of atrial fibrillation development


    Researchers have investigated determinants of atrial fibrillation
    development in patients with hypertrophic cardiomyopathy.

    According to recent research published in the American Journal of Cardiology
    , "Predictors of the development of atrial fibrillation (AF) in patients who
    have hypertrophic cardiomyopathy (HC) have not been extensively studied,
    although, in these patients, AF contributes to the exacerbation of symptoms and
    the development of heart failure. [Our] study determined the role of left atrial
    (LA) function in the development of AF in patients who have HC."

    M.A. Losi and colleagues of the University of Naples described their study,
    "One hundred fifty consecutive patients who had HC, had no history of AF, and
    who were followed for 5.2±2.9 years constituted the study population. Using
    M-mode echocardiography, we measured LA function as global LA fractional
    shortening and LA diameter. LA volume was measured from 2-dimensional 4-chamber
    views by the method of disks."

    "During follow-up, 20 patients developed AF. LA function was an independent
    predictor of AF (odds ratio 0.716, p=<0.001), whereas LA diameter and volume
    were predictors in addition to age. Kaplan-Meier analysis showed that LA
    dysfunction carried a high risk of AF," the researchers reported.

    They concluded, "Thus, in patients who have HC, LA function is a strong
    predictor of AF development and is independent of age."

    Losi and colleagues published their study in American Journal of Cardiology
    (Determinants of atrial fibrillation development in patients with hypertrophic
    cardiomyopathy. Am J Cardiol, 2004;94(7):895-900).

    For additional information, contact S. Betocchi, University of Naples
    Federico II, Department of Clinical Medicine, School of Medicine, Via S Pansini
    5, I-80131 Naples, Italy.
    Knowledge is power ... Stay informed!
    YOU can make a difference - all you have to do is try!

    Dx age 12 current age 46 and counting!
    lost: 5 family members to HCM (SCD, Stroke, CHF)
    Others diagnosed living with HCM (or gene +) include - daughter, niece, nephew, cousin, sister and many many friends!
    Therapy - ICD (implanted 97, 01, 04 and 11, medication
    Currently not obstructed
    Complications - unnecessary pacemaker and stroke (unrelated to each other)