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Zargis medical


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  • Zargis medical

    This data was collected at the last HCMA meeting!

    PRINCETON, N.J., Nov. 5 /PRNewswire-FirstCall/ - Researchers at Zargis
    Medical Corp., a majority-owned subsidiary of Speedus Corp. (Nasdaq: SPDE),
    announced today the results of a clinical study that demonstrated that a
    computer-assisted heart sounds analysis algorithm could identify those
    patients flagged by a cardiologist as having apical systolic murmurs that were
    louder on standing than reclining, a cardinal sign of obstructive HCM. HCM is
    implicated in one third of the cases of sudden cardiac death in young
    The full report of this study will appear in the forthcoming volume of the
    Texas Heart Institute Journal.
    The study involved twelve volunteer subjects who had been previously
    diagnosed with HCM, of which four reported obstructive HCM. Twenty-second
    recordings were obtained at each of four standard auscultatory locations in
    two postures: standing and reclining. Detailed auscultatory findings were
    derived by listening to the heart sound recordings by a cardiologist who was
    blinded to the study design. The recordings were analyzed by a computer
    algorithm that detects and identifies heart sounds and murmurs, and provides
    quantitative measures of the heart sounds. The algorithm results were compared
    with the auscultatory findings provided by the cardiologist.
    A high degree of concordance between the cardiologists' auscultatory
    findings and computer analyses was obtained. The systolic energy was found to
    correlate well with judgments of the relative loudness of murmurs in different
    postures. Those three subjects which were flagged by the cardiologist as
    having apical systolic murmurs that were louder on standing, were identified
    by the algorithm as having apical systolic murmurs with higher systolic
    energies in the standing posture.
    These results demonstrate that there are detectable acoustic features of
    heart sound recordings that are associated with auscultatory findings of
    obstructive HCM.
    According to Managing Director John Kallassy, "There is a clear and
    immediate need for a cost effective screening method that could help to
    identify young athletes at risk of sudden cardiac death due to HCM. This
    result holds promise of developing a cost-effective and readily available test
    for screening young athletes."

    About Zargis Medical Corp.
    Zargis Medical Corp. was formed in January 2001 when Siemens Corporate
    Research Inc., a subsidiary of Siemens AG (NYSE: SI), and Speedus Corp.
    (Nasdaq: SPDE) co-invested in Zargis to further develop and commercially
    market an advanced acoustic technology for detecting abnormalities identified
    through analysis of heart sounds. Based in Princeton, New Jersey, Zargis is
    developing advanced diagnostic decision support products and services for
    primary care physicians, cardiologists and other healthcare professionals.
    For additional information on Speedus Corp. or Zargis Medical, contact
    John Kallassy, 718.567.4358, [email protected], or visit their websites at
    http://www.speedus.com and http://www.zargis.com.
    For additional information on Siemens Corporate Research, visit their
    website at http://www.scr.siemens.com.

    Statements contained herein that are not historical facts, including but
    not limited to statements about the Company's product, corporate identity and
    focus, may be forward-looking statements that are subject to a variety of
    risks and uncertainties. There are a number of important factors that could
    cause actual results to differ materially from those expressed in any
    forward- looking statements made by the Company, including, but not limited
    to, the continuing development of the Company's sales, marketing and support

    SOURCE Zargis Medical Corp.
    Knowledge is power ... Stay informed!
    YOU can make a difference - all you have to do is try!

    Dx age 12 current age 46 and counting!
    lost: 5 family members to HCM (SCD, Stroke, CHF)
    Others diagnosed living with HCM (or gene +) include - daughter, niece, nephew, cousin, sister and many many friends!
    Therapy - ICD (implanted 97, 01, 04 and 11, medication
    Currently not obstructed
    Complications - unnecessary pacemaker and stroke (unrelated to each other)

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