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HEADLINE: HCM: Location of hypertrophy a factor...

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  • HEADLINE: HCM: Location of hypertrophy a factor...

    Copyright 2003 Cardiovascular Week via NewsRx.com and NewsRx.net
    Cardiovascular Week

    May 19, 2003

    SECTION: EXPANDED REPORTING; Pg. 21

    LENGTH: 392 words

    HEADLINE: HYPERTROPHIC CARDIOMYOPATHY: Location of hypertrophy a factor
    affecting right ventricular diastolic filling

    BODY:
    Location of the myocardial hypertrophy of the left ventricle is a significant
    factor affecting the right ventricular diastolic filling in patient with
    nonobstructive hypertrophic cardiomyopathy.

    "We examined whether differences in the location of myocardial hypertrophy
    influence the right ventricular diastolic function in patients with non-
    obstructive hypertrophic cardiomyopathy using cineanglography.

    "Biplane right ventriculography was performed in 34 subjects (normal=14,
    asymmetric septal hypertrophy=9, apical hypertrophy=11) during cardiac
    catheterization.

    "In patients with asymmetric septal hypertrophy, compared with apical
    hypertrophy and normal groups, the indices of the right ventricular diastolic
    function including right ventricular peak filling rate and filling fraction of
    rapid filling phase were lower and the time to peak filling rate was prolonged,"
    scientists in Japan report.

    "But in patients with apical hypertrophy, these indices were not
    significantly different compared with normal. There were no differences in right
    ventricular ejection fraction and cardiac index among the three groups," wrote
    K. Komaki and colleagues, Tohoku University, Graduate School of Medicine.

    The researchers concluded: "These data suggest that the location of the
    myocardial hypertrophy of the left ventricle is a significant factor affecting
    the right ventricular diastolic filling in non-obstructive hypertrophic
    cardiomyopathy."

    Komaki and colleagues published their study in Tohoku Journal of Experimental
    Medicine (Varieties of right ventricular diastolic function in patients with
    non-obstructive hypertrophic cardiomyopathy. Tohoku J Exp Med,
    2003;199(1):49-57).

    For additional information, contact K. Shirato, Tohoku University, Graduate
    School of Medicine, Department Cardiovascular Med, Aoba Ku, 1-1 Seiryomachi,
    Sendai, Miyagi 9808574, Japan.

    The publisher's contact information for the Tohoku Journal of Experimental
    Medicine is: Tohoku University Medical Press, School of Medicine, Sendai,
    980-77, Japan.

    The information in this article comes under the major subject areas of
    Angiology, Cardiology and Neurology.

    This article was prepared by Cardiovascular Week editors from staff and other
    reports.

    http://www.NewsRx.net

    LOAD-DATE: May 16, 2003
    Thanks, Tim
    Forum Administrator

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