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Toogoofy317 non-obstructed hcm, AICD 11-01-02 and 10-6-05
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  • Persantine

    Does anyone know much about persantine? We have started this med in hopes to help the microvascular disease that aggravates my HCM. We are starting to run out of meds. If this doesn't work then they want to experiment with a tricyclic anti-depressant that has vasodilation as a side effect. With my past that is the last thing I want to be on and they said it had a lot of side effects.

    Back to the Persantine, I was looking up the med and didn't find a lot. Mainly its uses in stress testing. If anyone has taken this med any feed back would be appreciated or any info at all.

    Mary S.

  • #2
    Mary---With all the oddities of meds and their side effects, I hope this one works for you. My thoughts and best wishes are with you.



    • #3
      You done been looking atta wrong name. Give it a shot under Dipyridamole.

      Patient Education Information


      DIPYRIDAMOLE (dye-peer-ID-a-mole)
      DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.

      INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding.

      If overdose is suspected, contact your local poison control center or emergency room immediately.

      Follow the directions for using this medicine provided by your doctor.

      TAKE THIS MEDICINE ON AN EMPTY STOMACH at least 1 hour before or 2 hours after eating. THIS MEDICINE MAY BE TAKEN WITH FOOD if it upsets your stomach. STORE THIS MEDICINE at room temperature in a tightly-closed container, away from heat and light. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

      BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are using this medicine. THIS MEDICINE MAY CAUSE dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. IF DIZZINESS OCCURS, sit up or stand up slowly. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE either prescription or over-the-counter, check with your doctor or pharmacist. THIS MEDICINE IS EXCRETED IN BREAST MILK. IF YOU ARE OR WILL BE BREAST-FEEDING while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.

      This medicine is a platelet inhibitor used to prevent clot formation in the blood. It may also be used to treat other conditions as determined by your doctor.

      SIDE EFFECTS, that may go away during treatment, include dizziness, stomach discomfort, headache, or rash. If they continue or are bothersome, check with your doctor. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

      Copyright 2003 Facts and Comparisons
      Database Version 03.1
      The information in this monograph is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This information is generalized and is not intended as specific medical advice. If you have questions about the medicines you are taking or would like more information, check with your doctor, pharmacist, or nurse.

      You might also be interested in checking out –



      Happy reading,


      • #4
        Mary ,

        I do not know about Persantine but, when I worked in psych , we had to be very carefull that we did not give cardiac risk patients any tricyclic antidepressants. We had known experience with them causing hypertension , heart attacks and EKG changes. I know that you BP runs low and HCM hearts are different from coronary insufficciency heart conditions but isn't small vessel disease somewhat related to this coronary and vascular insufficiency.

        Just make sure your doc is very up on the effects and how they will relate to your "unique heart" situation.

        Best to you.

        Dx @ 47 with HOCM & HF:11/00
        Guidant ICD:Mar.01, Recalled/replaced:6/05 w/ Medtronic device
        Lead failure,replaced 12/06.
        SF lead recall:07,extracted leads and new device 2012
        [email protected] Tufts, Boston:10/5/03; age 50. ( [email protected] 240 mmHg ++)
        Paroxysmal A-Fib: 06-07,2010 controlled w/sotalol dosing
        Genetic mutation 4/09, mother(d), brother, son, gene+
        Mother of 3, grandma of 3:Tim,27,Sarah,33w/6 y/o old Sophia, 5 y/o Jack, Laura 34, w/ 5 y/o old Benjamin


        • #5
          I hear ya Pam,

          It is very tiring being a guinea pig let me tell you. But they are running out of options and they are trying everything to keep me working. They said if the Persatine didn't work then the tri-cyclic anti-depressent would be the last ditch effort. But, before I started it I will assure you much research will be done on my part and a call to Dr. Maron. Which I plan on calling him tomorrow to arrange a confrence call with my local guy.

          The chest pain seems to be abating a bit but I've noticed an increased amount of SOB. Can persantine cause that? I've also got a rash on my left arm and elbow. I can't help but wonder if these correlate.


          Mary S.


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