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Authorized Generic for Toprol-XL


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  • Authorized Generic for Toprol-XL

    For over 5 years now I have been using the authorized generic of Toprol-XL per my cardiologist's recommendation (Cleveland Clinic). I take 100 MG tabs twice a day. When I was originally diagnosed I was put on 50 MG once a day and took any generic. As my HOCM symptoms worsened my dosage increased. At 100 MG once a day (any generic) I started to experience severe insomnia. I was referred to Cleveland Clinic where I had a myectomy and an ICD implanted. I was told only to take the authorized generic and even though my dosage increased, I no longer experienced insomnia.

    My understanding is that both Toprol-XL and the authorized generic, Metoprolol ER Succinate, are still made by AstraZeneca in Sweden but are distributed by different companies. In around 2016 I was told that the authorized generic distributor changed from Par to Lannett. I confirmed then that it was the same product and had no problems. Recently, I had trouble getting the prescription filled. Walgreens said their supplier could not get it from Lannett anymore. I contacted Lannett and they said they no longer distribute it - no other information. I tried contacting Aralez who was the brand name distributor in North America but they seem to be out of business. I contacted AstraZeneca and they said they "divested" the drug and seemed to believe that they no longer made it even through their phone tree recognized the drug by name. They referred me to New American Therapeutics who seem to only have Toprol XL in their portfolio. They said that they are no longer offering an authorized generic. But they confirmed that Toprol XL is made by AstraZeneca in Sweden.

    I know Cleveland Clinic can sometimes be old school in their instance on certain things, but my experience with this drug is that the manufacturer does matters. Currently I am trying to get my insurance company to cover the brand name. The difference for a 90 day supply is something like $350 without insurance.

    Has anyone else experienced any issues with generics of this drug or trouble obtaining the authorized generic?

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